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Principles of Neural Science 4th Edition

4.8 4.8 out of 5 stars 671 ratings

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A Doody's Core Title for 2011!

5 STAR DOODY'S REVIEW!
"This is a simply wonderful book that makes accessible in one place all the details of how the neuron and brain work. The writing is clear. The drawings are elegant and educational. The book is a feast for both the eye and mind. The richness, the beauty, and the complexity of neuroscience is all captured in this superb book."--
Doody's Review Service

Now in resplendent color, the new edition continues to define the latest in the scientific understanding of the brain, the nervous system, and human behavior. Each chapter is thoroughly revised and includes the impact of molecular biology in the mechanisms underlying developmental processes and in the pathogenesis of disease. Important features to this edition include a new chapter - Genes and Behavior; a complete updating of development of the nervous system; the genetic basis of neurological and psychiatric disease; cognitive neuroscience of perception, planning, action, motivation and memory; ion channel mechanisms; and much more.
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Editorial Reviews

Review

"This is a simply wonderful book that makes accessible in one place all the details of how the neuron and brain work. The writing is clear. The drawings are elegant and educational. The book is a feast for both the eye and mind. The richness, the beauty, and the complexity of neuroscience is all captured in this superb book." "5 Stars!" (Doody's 2001-11-01)

About the Author

McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Product details

  • Publisher ‏ : ‎ McGraw-Hill Medical; 4th edition (January 5, 2000)
  • Language ‏ : ‎ English
  • Hardcover ‏ : ‎ 1414 pages
  • ISBN-10 ‏ : ‎ 0838577016
  • ISBN-13 ‏ : ‎ 978-0838577011
  • Item Weight ‏ : ‎ 7.55 pounds
  • Dimensions ‏ : ‎ 8.75 x 2.25 x 11.25 inches
  • Customer Reviews:
    4.8 4.8 out of 5 stars 671 ratings

Customer reviews

4.8 out of 5 stars
4.8 out of 5
671 global ratings

Top reviews from the United States

Reviewed in the United States on April 14, 2013
This is a massive volume that provides a detailed sense of "the principles of neural science," the work's title. Basic statistics: the book weighs about nine pounds; it is 1709 pages long; it has 67 chapters; there are six appendices; 79 authors are involved; the book is divided up into 9 parts, each with numerous chapters. To compare, the fourth edition (published in 2000) had about 1400 pages. This volume is not meant for a general audience, but it is a wonderful resource for those who can work their way through its many chapters. I have found earlier volumes in this series very helpful for one part of my academic research agenda (the political implications of human biology).

Let's take a look at the structure of the volume, to illustrate the substance of the book. Part I provides an overall perspective on the scope of the book. The chapters examine the role of the brain in behavior, a summary of nerve cells and their function, and the relationship between genes, the brain, and behavior. With this serving as an introduction, Part II goes on to examine cells and the molecular biology of the neuron. Among subjects covered: The structure and nature of neurons and glial cells (which support neurons) and the electrical properties of neurons. Part III focuses on synapses, which provide for communication between and among neurons. How do synapses operate? What are chemical and electrical modes of operation? What is the role of neurotransmitters? Finally, this section considers diseases of the nerve and systems that they support.

Part IV is very important for my research interests--"The Neural Basis of Cognition." How does the brain and its structure affect cognition Chapter 15 describes the structure of the central nervous system and how the cerebral cortex, for example, affects cognition. In the chapter is a discussion of how the cerebral cortex is organized by layers AND by columns. Other important chapters in this section include effects on cognitive functioning of the brain outside the cerebral cortex and how functional imaging of cognition works (and the limitations with the use of such technology).

Part V summarizes our understanding of perception, how we come to experience the world around us. Subjects? The somatosensory system, touch, pain, vision (with five chapters devoted to the subject), the inner ear, hearing, and smell and taste. Part VI? Movement. The chapters herein explore the various elements in making movement possible. We learn of the different brain areas and other support systems underlying movement and locomotion.

How do people process information? Part VII concentrates on this, and this segment is also of relevance for my own research interests. Part VIII targets development and emergence of behavior. The one chapter in this section that is most poignant to me is Chapter 59--"The Aging Brain." The chapter speaks to what we know of the effects of aging on the brain and its functioning. Finally, section IX, "Language, Affect, and Learning." These represent key issues of interest in our understanding of central features of being human.

This book is not something that most of us would skim. But it is a compendium that well illustrates what we know about the structure and function of the brain. For those interested in the subject, this is an important work.
24 people found this helpful
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Reviewed in the United States on January 12, 2024
The best neuroscience text; even this slightly older edition is outstanding.

Speedy delivery, very well packaged to protect unused textbook.
One person found this helpful
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Reviewed in the United States on September 16, 2019
I do not need this text (done with my education a long time ago), but read it for pure fun every now and then. Do not need it for work. Perhaps the fact that I read this when I feel like it, not when I must, increases the pleasure of experiencing it.

The text is a very thorough description of the current status of knowledge, including the current confusions in the minds of neuroscientists when it comes to "mind", "consciousness" and the like. I never stop being shocked how obviously smart people find "controversy" or that something is "unknown", when in other parts of the text they show clear answers.

For example, in chapter 17 Dr. Kandel describes how Penrose was able to establish the cortical representation of sensation by stimulating the cortex in awake patients and asking them what they felt, obviously demonstrating that stimulation of certain areas of the cortex brought specific things into the patients' consciousness, that they were then able to report verbally to the surgeon who was doing the stimulation. Yet, a few pages later in the text, Dr. Kandel writes about a fierce debate between philosophers of mind about the nature of consciousness "because it is difficult to see how consciousness might be explained in reductionist physical terms." Well, he just did, a few pages before that, by describing Penrose's experiment.

Puzzling.

But apart from a few such details this is the greatest text for anyone wishing to inform themselves about the function of the human brain.
12 people found this helpful
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Reviewed in the United States on February 7, 2024
Happy with the book
Reviewed in the United States on February 19, 2016
Wealth of Knowledge and Awesome Diagrams

The book Principles of Neural Science by Kandel et. al. has been a fantastic compliment to the class I’m currently enrolled in at Iowa State. The immense amount of knowledge contained in the book enhances my learning and has helped to develop my understanding of neural science. The diagrams in the book are well illustrated and display the contents of the book effectively. This is a required book for graduation in my discipline and is for advanced learners only. The subject matter within the book might be difficult to grasp without some prior knowledge of neural science.

The information in this book is outstanding and is unlike any other neural science textbook that I have read during my college career. With that said, the book is very “heavy”, in both weight and content. I haven’t weighed it myself, but it is the heaviest textbook I have had in my four years of college. However, with the relevant amount of information in the book, it is a price I’m willing to pay!

I would recommend this textbook for people seeking an advanced education in the field of neural science. The book has complicated information, but with the detailed diagrams and case studies provided, the reader gains a better understanding of neural science.
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DIPANKAR DAS
5.0 out of 5 stars Excellent one.
Reviewed in India on March 14, 2023
In research there is no end point of line, but we can accumulate huge extent of robust knowledge from this beautiful book in a singular point from where generate a crystal clear keen regular concept to understand our Nature.
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DIPANKAR DAS
5.0 out of 5 stars Excellent one.
Reviewed in India on March 14, 2023
In research there is no end point of line, but we can accumulate huge extent of robust knowledge from this beautiful book in a singular point from where generate a crystal clear keen regular concept to understand our Nature.
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2 people found this helpful
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Luc Wilson
5.0 out of 5 stars Perfect reference for any neuroscientist
Reviewed in Canada on January 30, 2020
The only neuroscience textbook most students will ever need, great reference book for the lab.
Ricardo Zavala
5.0 out of 5 stars Excelente libro de Neurociencias
Reviewed in Mexico on December 21, 2018
Es un libro de referencia en el área de neurociencias. Es ideal para estudiantes de esta área (neurofisiología) y para profesionales de la salud.

Totalmente recomendado, de fácil lectura y muy cómodo para leer (tamaño de letra y esquemas).
Este libro particularmente lo uso para el posgrado en Ciencias Fisiológicas y es un texto de consulta el cual explica de manera clara y concisa cada uno de los conceptos de la Neurofisiología y mecanismos básicos (moleculares, eléctricos, anatómicos).

Lo recomiendo ampliamente para estudiar Neurofisiología, ya sea que seas estudiante de neurociencias, biomédicas, o simplemente eres apasionado al tema.
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Ricardo Zavala
5.0 out of 5 stars Excelente libro de Neurociencias
Reviewed in Mexico on December 21, 2018
Es un libro de referencia en el área de neurociencias. Es ideal para estudiantes de esta área (neurofisiología) y para profesionales de la salud.

Totalmente recomendado, de fácil lectura y muy cómodo para leer (tamaño de letra y esquemas).
Este libro particularmente lo uso para el posgrado en Ciencias Fisiológicas y es un texto de consulta el cual explica de manera clara y concisa cada uno de los conceptos de la Neurofisiología y mecanismos básicos (moleculares, eléctricos, anatómicos).

Lo recomiendo ampliamente para estudiar Neurofisiología, ya sea que seas estudiante de neurociencias, biomédicas, o simplemente eres apasionado al tema.
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10 people found this helpful
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DC
5.0 out of 5 stars Muy recomendable!
Reviewed in Spain on July 15, 2020
¡Libro de alta calidad y muy interesante para todos los amantes de la neurociencia!
Francesca
5.0 out of 5 stars Excellant
Reviewed in the United Kingdom on February 18, 2020
This book is referenced in almost all of my neuroscience modules in college. Provides a good basis for all concepts, with clear diagrams and pictures. Packed to the brim with details.
Delighted with this purchase. It was in perfect condition, better than some of the copies present in my colleges library! Prompt delivery in addition.
One person found this helpful
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